The research group that makes up the Helminth Reference and Research Laboratory (RIHE) of the CNM-ISCIII works on different aspects of helminth immunobiology, taking advantage of recombinant DNA approaches, omics sciences, bioinformatics tools and biochemical assays. The research is basically oriented towards:

1.     The biochemical and molecular characterization of parasitic antigens of interest.
2.     The analysis of the immune response produced in the host against these antigens and the molecular mechanisms of   these diseases.
3.     To the development and improvement of diagnostic systems.
4.     The definition of helminth allergenic candidates.
5.     The design of possible vaccines and participation in helminthosis control and surveillance strategies.
6.     Search for antiparasitic drugs.
7.     Research into new therapeutic alternatives for autoimmune diseases using helminth molecules.

The group works on helminthosis projects caused by species of Taenia spp., Fasciola spp., Trichinella spp., Filarias, O. volvulus, Anisakis spp., Ancylostoma spp., Opisthorchis spp., Schistosoma spp. and with experimental models such as Nippostrongylus brasiliensis and Trichuris muris, among others.