We protect your health through science
Investigation
Human viruses of the herpesviridae family
Publications
Potential implication of azole persistence in the treatment failure of two haematological patients infected with Aspergillus fumigatus
Peláez-García de la Rasilla T, Mato-López A, Pablos-Puertas CE, González-Huerta AJ, Gómez-López A, Mellado E, Amich J. Journal of Fungi, 2023 Jul 30;9(8):805.
PUBMED DOIAspergillus fumigatus can exhibit persistence to the fungicidal drug voriconazole
Valero C., Á Mato-López, I J. Donaldson, A. Roldán, H. Chown, N. Van-Rhijn, S. Gago, T. Furukawa, A. Mogorovsky, R. Ben Ami, P. Bowyer, N. Osherov, T. Fontaine, G.H. Goldman, E. Mellado, M. Bromley and J. Amich. Microbiology Spectrum.2023 13;11(2):e0477022
PUBMED DOICOVID-19 Associated Pulmonary Aspergillosis (CAPA): Hospital or Home Environment as a source of life-threatening Aspergillus fumigatus infection?
Peláez-García de la Rasilla T, González-Jiménez I, García-Fernández Arroyo A, Roldán A, Carretero-Ares JL, Clemente-García M,, Martínez-Suarez M, Vázquez Valdés F, Melón-Garcia S, Mellado E, Sánchez-Nuñez ML on behalf HUCAPA group. Journal of Fungi, 2022 Mar 19;8(3):316.
PUBMED DOIAdditional Information
Our group is interested in infections caused by the 8 known human herpes, which are very important etiological agents due to the high rates of infection, as well as their morbidity and mortality, especially in situations in which the immune system is immature (pediatric disease), senescent (pathologies in advanced age) or immunocompromised (transplanted).
They form a very heterogeneous group, but once the infection occurs, it persists for life through its latency phases. The pathogenicity of alpha- and beta-herpesviruses is related to primary infection and its recurrences, but in gamma-herpesviruses their main pathogenicity lies in their ability to produce tumors.
The main objective of the group is to respond to the medical problems caused by these infections from a multidisciplinary point of view, which includes virological, immunological and molecular aspects.
At present, the group's specific research objectives focus mainly on two topics:
Pathogenicity markers in congenital cytomegalovirus disease that modulate the immune system during infection and
Molecular characterization of the varicella zoster virus in cases of vaccine failure. The group's IP is part as a promoter partner of Spin-off: Virnóstica-ISCIII
Our group is interested in infections caused by the 8 known human herpes, which are very important etiological agents due to the high rates of infection, as well as their morbidity and mortality, especially in situations in which the immune system is immature (pediatric disease), senescent (pathologies in advanced age) or immunocompromised (transplanted).
They form a very heterogeneous group, but once the infection occurs, it persists for life through its latency phases. The pathogenicity of alpha- and beta-herpesviruses is related to primary infection and its recurrences, but in gamma-herpesviruses their main pathogenicity lies in their ability to produce tumors.
The main objective of the group is to respond to the medical problems caused by these infections from a multidisciplinary point of view, which includes virological, immunological and molecular aspects.
At present, the group's specific research objectives focus mainly on two topics:
Pathogenicity markers in congenital cytomegalovirus disease that modulate the immune system during infection and
Molecular characterization of the varicella zoster virus in cases of vaccine failure. The group's IP is part as a promoter partner of Spin-off: Virnóstica-ISCIII