Toxoplasmosis and intestinal protozoa
Publicaciones destacadas
Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessmen
U. Voguel, M.K. Taha, J.A. Vázquez, J. Findlow, H. Claus, P. Stefanelli, D.A. Caugant, P. Kriz, R. Abad, S. Bambini, A. Carannante, A.E. Deghmane, C. Fazio, M. Frosch, G. Frosi, S. Gilchrist, M.M. Giulani, E. Hong, M. Ledroit, P.G. Lovaglio, J. Lucidarme, M. Musilek, A. Muzzi, J. Oksne, F. Rigat, L. Orlandi, M. Stella, D. Thompson, M. Pizza, R. Rappuoli, D. Serruto, M. Comanducci, G. Boccadifuoco, J.J. Donnely, D. Medini, R. Borrow. “Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment”. Lancet Infect Dis. 2013 May; 13(5): 416-25.
PUBMED DOIHepatitis C Virus Influences HIV-1 Viral Splicing in Coinfected Patients
Martínez-Román P; López-Huertas MR; Crespo-Bermejo C; et al; Briz V (AC). (16/15). 2020. Hepatitis C virus influences HIV-1 viral splicing in coinfected patients JOURNAL OF CLINICAL MEDICINE. MDPI. ISSN 2077-0383.
DOIPublic health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey
Harris SR, Cole MJ, Spiteri G, Sánchez-Busó L, Golparian D, Jacobsson S, Goater R, Abudahab K, Yeats CA, Bercot B, Borrego MJ, Crowley B, Stefanelli P, Tripodo F, Abad R, Aanensen DM, Unemo M, Euro-GASP study group. “Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe”. Lancet Infect Dis. 2018 Jul; 18(7):758-768.
PUBMED DOIHCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients
Brochado-Kith; Martínez I; Berenguer J; et al; Fernández-Rodríguez A (AC); Resino S. (11/12). 2021. HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients. Journal of Biomedical Sciences. Springer Nature. 28-1.
DOIContent with Investigacion .
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Isabel de Fuentes Corripio
Jefa de Unidad, Investigador Titular OPIS
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David González Barrio
Investigador contratado
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Marta Hernández de Mingo
Colaborador I+D+I
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David Carmena Jiménez
Investigador Doctor distinguido
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Aly Salimo Omar Muadica
Becario pre-doctoral
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Begoña Bailo Cardoso
Técnico de Laboratorio
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María Aguilera
Técnico de laboratorio
List of staff
Información adicional
Our group carries out research studies in the diagnosis, reference and epidemiology of zoonoses and emerging diseases, both indigenous and imported, caused by protozoa. Coordinates the study in the human field with the relevance of the animal field and the environment (One Health initiative), with special interest in Toxoplasmosis, a highly prevalent zoonosis (WHO lists it as the 3rd food-borne zoonosis in Europe), presents a complex epidemiological cycle and causes neurological, ocular and systemic symptoms. We carry out diagnostic and characterization studies of Toxoplasma gondii from human and animal cases, to obtain greater epidemiological information and analyze the possible relationship with virulence and pathology.
Cryptosporidium, Giardia, Blastocystis and Entamoeba histolytica cause gastrointestinal diseases, affecting children, immunosuppressed people and travelers. They can cause outbreaks. We develop diagnostic and characterization studies of isolates from humans and animals, from different areas and countries, to establish the presence of the main species and genotypes and the epidemiological situation. We are beginning the study of associations between these parasites and the intestinal microbiota.
The pathogenic Free-Living Amoebas, Acanthamoeba, Naegleria fowleri and Balamuthia mandrillaris, cause emerging diseases, highlighting the importance of the environment in transmission. They cause underdiagnosed neurological and ocular cases. The diagnostic and genotyping study of human and animal isolates that we are carrying out aims to establish the real prevalence, transmission routes and epidemiology.